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Carvaljal syndrome

An arrhythmogenic cardiomyopathy syndrome with a striate (linear) or focal pattern of palmoplantar keratoderma and woolly hair.

Pachyonychia congenita

A genetic disorder characterized by hypertrophic nail dystrophy (thickened nails) and painful, focal palmoplantar keratoderma over pressure points.

Richner-Hanhart syndrome

Also known as tyrosinemia type II, this is a metabolic disorder causing painful, focal, hyperkeratotic plaques on the palms and soles, along with corneal ulcers.

Striate keratoderma

A pattern of keratoderma with linear bands of hyperkeratosis extending from the palm onto the fingers.

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