How are antibiotics used to treat acne?

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Bacteria, such as Propionibacterium acnes, that are naturally present on the human skin, contribute to the formation of acne lesions (see our post on the causes of acne). Antibiotics are effective treatments for acne and are believed to work both by reducing the quantity of bacteria on the skin surface and thorugh additional anti-inflammatory effects.

Antibiotics can be used topically (directly on the skin as creams, gels or ointments). Antibiotics used in this way include erythromycin (for example Zineryt) and clindamycin (for example duac gel or dalacin T). Duac is a combination treatment that also contains benzoyl peroxide.

Antibiotic tablets will usually be taken for a course of a few months of treatment. The most common are tetracyclines, for example, lymecycline are usually well tolerated. Other antibiotics that can be used include erythromycin or trimethoprim. Antibiotic tablets can be very effective treatments for mild or moderate acne, however acne can recur when they are discontinued.

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Dr. Magnus Lynch, Consultant Dermatologist

About Dr Magnus Lynch

I am a London-based Consultant Dermatologist and Dermatological Surgeon. My NHS practice is at Guy's Hospital and is focused on Mohs micrographic surgery and the treatment of complex skin cancers. My private practice additionally focuses on laser treatments, regenerative dermatology, rosacea, acne, pigmentation and scarring. I have particular expertise in the diagnosis and treatment of skin cancer, including minimally-invasive techniques, Mohs micrographic surgery, and facial reconstructive surgery. I studied at the Universities of Cambridge and Oxford, and completed my dermatology training and Mohs fellowship at the prestigious St John’s Institute of Dermatology. I graduated from medical school in 2003 and have worked exclusively in Dermatology since 2012.

I lead a research team at King’s College London investigating the molecular biology of skin cancer and skin cancer diagnostics, and I constantly aim to translate the latest findings into better patient care. You can learn more about my Research.

In recent years I have been involved in Media Appearances, including the Channel 5 series 'Skin A&E', where I perform skin surgeries and treat various skin conditions. Filming for the next series has recently completed and the series will be released later in 2025.

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