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Acrodermatitis continua of Hallopeau

A rare, chronic, sterile pustular eruption starting on a single digit, leading to nail destruction, skin atrophy, and bone loss.

Acropustulosis of infancy

A recurrent, intensely itchy eruption of vesicles and pustules specifically on the palms and soles of infants, distinct from other causes by its age group and recurrence.

Dyshidrotic eczema

Presents as small, deep-seated, "tapioca-like" vesicles on the palms, soles, and sides of fingers, which can become pustular but start as clear blisters.

Hand foot and mouth disease

A viral illness causing oral ulcers and a rash of oval-shaped vesicles, which may become pustular, on the hands and feet.

Palmoplantar pustulosis

A chronic condition defined by crops of sterile, deep-seated yellow-brown pustules on the palms and soles, which then dry up and form brown scaly spots.

Tinea

A fungal infection of the feet (tinea pedis) that can present with an inflammatory vesicular or pustular eruption, often accompanied by scaling and maceration between the toes.

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