A photosensitive eruption featuring intensely itchy papules and nodules that can erode and form hemorrhagic crusts and blisters on sun-exposed skin.
An eczematous reaction to an allergen characterized by intensely itchy vesicles and bullae on an erythematous base, often in a linear or geometric pattern.
A neutrophilic dermatosis that can present with tender, erythematous plaques topped with tense, and sometimes hemorrhagic, bullae.
A drug-induced eruption that can manifest as tense bullae on normal-appearing or erythematous skin, such as in a bullous fixed drug eruption.
Characterized by targetoid lesions with a central bulla or crust, typically on acral sites, often triggered by herpes simplex virus infection.
A superficial bacterial infection causing flaccid, fragile bullae with clear or cloudy fluid that rupture easily, leaving a thin, varnish-like crust.
A rare variant where tense bullae arise directly on pre-existing violaceous, flat-topped papules and plaques of lichen planus.
An autoimmune disease of the elderly causing large, tense, fluid-filled bullae on erythematous or urticarial plaques, which are intensely pruritic.
An inflammatory fungal infection, typically on the feet, that presents with vesicles and bullae in addition to typical scaling and maceration.
A severe form of leukocytoclastic vasculitis where palpable purpura progresses to form hemorrhagic bullae and necrotic ulcers.
An autoimmune blistering disease in children characterized by large, tense bullae arranged in annular "cluster of jewels" or "rosette" patterns.
An intensely pruritic, autoimmune blistering disease linked to celiac disease, featuring symmetric groups of small vesicles and papules on extensor surfaces like elbows and knees.
Spontaneous, non-inflammatory, tense bullae that appear suddenly on the feet and hands of diabetic patients, resembling friction blisters but without known trauma.
An eczematous reaction presenting as small, deep-seated, "tapioca-like" vesicles on the palms, soles, and sides of fingers.
A group of inherited disorders where blisters and erosions form in response to minimal friction or trauma, present from birth or infancy.
An acquired autoimmune disease of adulthood with skin fragility and non-inflammatory bullae in trauma-prone areas, resembling porphyria cutanea tarda.
Clear fluid-filled bullae that form at sites of repeated rubbing or pressure, with a clear history of mechanical cause.
A viral infection causing a cluster of small, uniform vesicles on an erythematous base that progress to pustules and then crust over.
A rare autoimmune disease with two main subtypes: one resembling Sneddon-Wilkinson disease with flaccid pustules in an annular pattern, and another with vesicopustules on erythematous skin.
An inflammatory response to an insect bite that can form a central papule surrounded by an urticarial flare, sometimes with a prominent central bulla.
An autoimmune blistering disease characterized by the unique arrangement of tense vesicles and bullae in an annular "cluster of jewels" pattern.
A malformation of lymphatic vessels presenting as clusters of deep-seated, tapioca-like vesicles (frog spawn appearance) that contain clear or pinkish fluid.
Caused by sweat duct obstruction at the most superficial level, presenting as tiny, clear, dewdrop-like, non-inflamed vesicles that rupture easily.
An autoimmune disease primarily causing blisters and erosions on mucous membranes (oral, ocular) that heal with significant scarring.
Tense, non-inflammatory bullae that arise on skin with massive, dependent edema, typically on the lower legs.
Blisters that can arise as a side effect of psoralen plus UVA therapy, often on the feet or areas of high UVA dosage.
An intensely pruritic autoimmune blistering disease specific to pregnancy, starting with urticarial papules and plaques that evolve into tense bullae, often beginning around the umbilicus.
An autoimmune disease with superficial, fragile bullae that rupture very easily, leading to shallow erosions and a characteristic "cornflake-like" scale and crust, often on the face and upper trunk.
A severe autoimmune disease characterized by flaccid, easily ruptured bullae and painful erosions that almost always begins in the oral mucosa.
A non-allergic reaction to a drug plus UV light, resembling an exaggerated sunburn with erythema, edema, and bullae confined to sun-exposed areas.
An allergic contact dermatitis to urushiol oil, classically presenting as linear streaks of intensely itchy vesicles and bullae.
The most common photodermatosis, presenting as a delayed, itchy eruption of various morphologies (papules, plaques, vesicles) on sun-exposed skin after UV exposure.
A metabolic disorder causing skin fragility, vesicles, and bullae on sun-exposed areas, particularly the hands, which heal slowly with milia and hyperpigmentation.
A bulla that forms over a bony prominence due to prolonged pressure and shear forces, often in obtunded or immobile patients.
A drug-induced condition that clinically mimics porphyria cutanea tarda with skin fragility and bullae on sun-exposed skin, but with normal porphyrin levels.
Reactivation of the varicella-zoster virus, causing a painful, unilateral eruption of vesicles on an erythematous base in a specific dermatomal distribution.
A severe mucocutaneous reaction, often to drugs, characterized by widespread dusky red macules, atypical target lesions, and bullae that lead to epidermal detachment of <10% of body surface area.
The most severe form of drug-induced skin reaction, with widespread, full-thickness epidermal necrosis and detachment affecting >30% of the body surface area, resembling a severe burn.
