A genetic zinc deficiency disorder causing a distinct triad of periorificial and acral dermatitis with vesiculobullous and eczematous lesions, alopecia, and diarrhea.
A form of epidermolytic ichthyosis present at birth with generalized erythema, blistering, and peeling, which later develops into hyperkeratosis.
A superficial bacterial infection causing flaccid, clear bullae that rupture easily, commonly seen in the diaper area of neonates.
A form of cutaneous mastocytosis where rubbing the skin causes large blisters and hives (Darier's sign) due to massive histamine release from mast cells.
Rare in children, this presents as large, tense, pruritic bullae on erythematous or normal-looking skin, similar to the adult form.
A rare disorder that can present at birth with a widespread eruption of reddish-brown papules that may be vesicular or pustular, resembling a viral exanthem.
A rare condition present at birth with widespread erosions, vesicles, and crusting that heals with characteristic reticulated, supple scarring.
Presents in the neonatal period with a characteristic widespread vesiculobullous eruption, especially on the palms and soles, along with other systemic signs.
An inherited disorder characterized by blister formation in response to minimal mechanical trauma, with severity and location depending on the specific subtype.
A genetic ichthyosis presenting at birth with blistering and erythroderma that evolves into severe, verrucous hyperkeratosis, especially in flexures.
A genetic disorder with four cutaneous stages, the first of which is a linear or whorled pattern of inflammatory vesicles and bullae present at birth or shortly after.
A term for widespread blistering and peeling of the skin at birth, which can be a presentation of several underlying genetic blistering diseases.
An autoimmune blistering disease in children, often localized to the vulvar area or feet, presenting with tense bullae.
A rare genetic disorder causing acral blistering in infancy, followed by progressive poikiloderma (atrophy, telangiectasias, and pigment changes) and photosensitivity.
The most common autoimmune blistering disease in children, characterized by tense bullae arranged in an annular "cluster of jewels" pattern.
Congenital erythropoietic porphyria can cause photosensitivity with blistering, skin fragility, and red-stained urine and teeth in infants.
A toxin-mediated disease causing widespread erythema, followed by the formation of large, flaccid bullae and exfoliation of the epidermis in sheets, sparing the mucous membranes.
Benign, non-inflammatory bullae found on the hands, wrists, or lips of newborns, resulting from vigorous sucking in utero.
A severe drug reaction with widespread, dusky red macules and bullae leading to full-thickness epidermal detachment, often with severe mucosal involvement.
A form of cutaneous mastocytosis presenting as reddish-brown macules and papules that urticate and may blister when rubbed (Darier's sign).