A persistent, painless, symmetric bluish discoloration of the hands and feet that worsens with cold exposure.
Presents as tender, purplish papules and plaques on acral sites in the cold, but is specifically associated with underlying lupus erythematosus.
Antibodies that cause red blood cells to clump in the cold, leading to acrocyanosis and sometimes Raynaud's phenomenon or skin necrosis.
The destruction of red blood cells upon rewarming after cold exposure, which can cause hemoglobinuria and other systemic symptoms, but few primary skin signs.
Inflammation of subcutaneous fat after cold exposure, presenting as indurated, tender, erythematous nodules, classically on the cheeks of children ("popsicle panniculitis").
Characterized by the rapid onset of pruritic wheals (hives) and angioedema on skin exposed to cold.
A condition where proteins precipitate in the cold, leading to purpura, skin necrosis, and livedo reticularis.
A vasculitis caused by immune complexes that precipitate in the cold, classically presenting with palpable purpura on the lower extremities, arthralgias, and weakness.
A mottled, lace-like, purplish vascular pattern on the skin that becomes more prominent with cold exposure.
Also known as chilblains, this presents as painful, itchy, red to purple inflammatory papules and nodules on acral sites (fingers, toes, ears) after exposure to cold, damp conditions.
A specific form of friction- and cold-induced dermatitis in rowers, causing painful, purpuric plaques on the dorsum of the hands.
A vasospastic disorder causing a characteristic triphasic color change (white, then blue, then red) in the digits in response to cold or stress.
