A common skin cancer that can present as a "rodent ulcer," a slowly enlarging, pearly papule with telangiectasias that centrally ulcerates and destroys tissue.
Mucocutaneous leishmaniasis (espundia) causes devastating destruction of the nasal septum and surrounding soft tissue.
Lepromatous leprosy can lead to infiltration and collapse of the nasal bridge, creating a "saddle-nose deformity".
A form of cutaneous tuberculosis that can cause progressive, destructive, reddish-brown "apple-jelly" nodules on the face, especially the nose.
An older term for a type of lymphoma (nasal NK/T-cell) that causes progressive, ulcerative destruction of the nose and palate.
An aggressive fungal infection in immunocompromised or diabetic patients, starting in the sinuses and rapidly causing a black necrotic eschar on the palate or nose.
An aggressive lymphoma causing nasal obstruction, ulceration, and progressive destruction of the nose, sinuses, and palate.
A chronic bacterial infection (Klebsiella rhinoscleromatis) that causes woody, nodular induration and destruction of the nose and upper respiratory tract.
Paracoccidioidomycosis can cause destructive ulcerative lesions with a "mulberry-like" surface around the mouth and nose.
A skin cancer that can form a large, indurated, ulcerative, and fungating mass that invades and destroys underlying structures.
Tertiary syphilis can cause a destructive granulomatous lesion called a gumma, which can perforate the nasal septum or palate.
Now known as Granulomatosis with Polyangiitis, this vasculitis classically causes nasal crusting, sinusitis, and collapse of the nasal bridge ("saddle-nose deformity").
A treponemal infection that can cause destructive lesions of the nose and palate (gangosa) in its tertiary stage.
