A diffuse palmoplantar keratoderma associated with characteristic knuckle pads and progressive sensorineural deafness.
Also known as hidrotic ectodermal dysplasia, this is a diffuse keratoderma combined with nail dystrophy and hypotrichosis (sparse hair).
A genetic keratoderma with a diffuse, yellowish, thickened appearance of the palms and soles, often with a "dirty" quality and a tendency for blistering.
A diffuse, sclerosing (hardening) keratoderma associated with nail abnormalities and an increased risk of squamous cell carcinoma.
A severe, progressive, diffuse keratoderma with a characteristic erythematous ("transgradiens") border extending onto the tops of the hands and feet.
A diffuse, non-epidermolytic keratoderma associated with a distinctive woolly hair texture and arrhythmogenic right ventricular cardiomyopathy.
A classic "tylosis" presenting as uniform, waxy, or ivory-colored diffuse thickening of the palms and soles with an erythematous border.
A severe, mutilating diffuse keratoderma with characteristic periorificial (around mouth, nose, anus) hyperkeratotic plaques.
A diffuse palmoplantar keratoderma associated with severe, early-onset periodontitis leading to premature loss of teeth.
A pattern of keratoderma where the thickening extends beyond the palmar/plantar surface onto the dorsal aspects of the hands and feet, as seen in Mal de Meleda.
A diffuse, honeycomb-patterned keratoderma accompanied by characteristic constricting bands around the digits (pseudoainhum) and starfish-shaped keratoses on knuckles.