A delayed-type hypersensitivity reaction that can show a prominent eosinophilic infiltrate along with spongiosis (edema in the epidermis).
A benign eruption in infants with annular erythematous patches that histologically show a characteristic perivascular eosinophilic infiltrate.
The classic eczema, which histologically can show a variable infiltrate of eosinophils, especially in chronic lesions.
An autoimmune blistering disease where the subepidermal blister is typically filled with and surrounded by a dense infiltrate of eosinophils.
Now known as Eosinophilic Granulomatosis with Polyangiitis, this is a systemic vasculitis characterized by asthma, high eosinophil counts, and skin lesions like purpura and nodules full of eosinophils.
This fungal infection can elicit a granulomatous reaction rich in eosinophils.
Many drug hypersensitivity reactions, especially DRESS syndrome, are characterized by a widespread rash and a significant eosinophilic infiltrate in the skin and blood.
An intensely pruritic eruption of sterile, urticarial follicular papules and pustules, with a histology showing a dense eosinophilic infiltrate specifically around hair follicles.
A benign plaque on the face characterized by a dense, mixed inflammatory infiltrate containing numerous eosinophils, separated from the epidermis by a clear zone.
A systemic disorder of prolonged, high-level eosinophilia that can cause various skin manifestations, including pruritic papules, nodules, and urticaria, all with dense eosinophilic infiltrates.
The classic histologic picture of an insect bite is a wedge-shaped, perivascular infiltrate containing numerous eosinophils.
A benign histiocytic proliferation in children, which can sometimes show a prominent number of eosinophils within the infiltrate of foamy histiocytes.
A chronic inflammatory disorder presenting as large subcutaneous masses in the head and neck, with a histology of lymphoid follicles, vascular proliferation, and marked tissue eosinophilia.
A hypersensitivity reaction to insect bites, common in children, presenting as recurrent crops of pruritic papules that histologically show spongiosis and an eosinophilic infiltrate.
A rare dermatosis of elderly men presenting as a widespread, pruritic, papular erythroderma with a characteristic "deck-chair" sign (sparing of skin folds) and peripheral eosinophilia.
Many parasitic infections, like strongyloidiasis or hookworm, can cause skin eruptions and are associated with a high blood and tissue eosinophil count.
The most common dermatosis of pregnancy, presenting as intensely pruritic urticarial papules and plaques, often within striae, with a perivascular infiltrate that may contain eosinophils.
A chronic, intensely itchy eruption of small papules in HIV patients, histologically similar to eosinophilic folliculitis or an insect bite reaction.
A benign reactive proliferation of lymphocytes that can mimic lymphoma, often with a prominent component of eosinophils, as seen in lymphocytoma cutis.
The inflammatory reaction to the scabies mite and its products is often rich in eosinophils.
While typically sparse, the perivascular infiltrate in common hives can sometimes contain a significant number of eosinophils.
A small vessel vasculitis where the vessel walls are infiltrated by neutrophils, but the surrounding dermis can have a heavy infiltrate of eosinophils.
Also known as eosinophilic cellulitis, this is characterized by edematous, erythematous plaques and a dramatic dermal infiltrate of eosinophils, often arranged around collagen bundles ("flame figures").
