A common cause of erythroderma, which may evolve from chronic, severe eczema and is intensely pruritic with marked lichenification.
Can rarely present as an exfoliative erythroderma, sometimes with or preceding the characteristic tense bullae.
Cutaneous T-cell lymphoma, particularly Sezary syndrome, is a classic cause of intensely pruritic, infiltrated erythroderma.
A severe photosensitive eczema that can progress to a persistent erythroderma on both sun-exposed and non-exposed skin.
Several forms of ichthyosis, like congenital ichthyosiform erythroderma, present at birth with generalized redness (erythroderma) and scaling.
A severe, widespread allergic contact dermatitis (e.g., to a textile dye or topical medication) can generalize to an exfoliative erythroderma.
A severe drug reaction characterized by a morbilliform eruption that progresses to erythroderma, accompanied by fever, facial edema, lymphadenopathy, and eosinophilia.
The most common cause of erythroderma in adults, presenting as a simple exfoliative dermatitis that appears weeks after starting a new medication.
Acute GVHD after a transplant can present as a morbilliform rash that becomes confluent, leading to a tender erythroderma.
A life-threatening hyperinflammatory state that can present with a non-specific erythrodermic rash along with fever and cytopenias.
A systemic disorder of eosinophilia that can cause an intensely pruritic erythroderma.
Rarely, generalized lichen planus can become confluent and result in a violaceous, exfoliative erythroderma.
Diffuse cutaneous mastocytosis can cause a thickened, doughy erythroderma that exhibits a dramatic Darier's sign (urtication on rubbing).
Also known as crusted scabies, this hyperinfestation in immunocompromised individuals leads to a generalized, crusted, hyperkeratotic erythroderma teeming with mites.
A rare dermatosis of elderly men presenting as a widespread, pruritic, papular erythroderma with a characteristic "deck-chair" sign (sparing of skin folds).
Erythroderma can be a rare sign of an underlying internal malignancy, particularly lymphoma or leukemia.
An autoimmune blistering disease associated with malignancy that can present with features of lichen planus and erythema multiforme, sometimes evolving into an erythroderma.
An autoimmune blistering disease that can present as an exfoliative erythroderma with superficial erosions and a "cornflake-like" scale, as the blisters are very fragile.
A classic cause of erythroderma characterized by a reddish-orange hue, islands of sparing (unaffected skin), and prominent follicular papules.
The most common cause of erythroderma in adults, where >90% of the body surface is covered by bright red, inflamed psoriatic skin, often with fine scale.
Rarely, sarcoidosis can present as a generalized, infiltrated, reddish-brown erythroderma.
A streptococcal infection causing a diffuse, erythematous "sandpaper" rash that can become confluent, accompanied by a strawberry tongue and fever.
A toxin-mediated disease in children causing diffuse, tender erythema followed by widespread superficial desquamation.
A typo for subacute cutaneous lupus erythematosus, which typically presents as annular or papulosquamous lesions, but rarely can become erythrodermic.
