Congenital CMV infection can present with a "blueberry muffin" rash (petechiae and purpura from dermal erythropoiesis) and fever.
A localized area of red, swollen, warm, and tender skin, often at the site of a break in the skin, accompanied by fever.
A highly contagious viral illness causing fever and a rash that progresses from macules to papules to characteristic "dewdrop on a rose petal" vesicles.
A mosquito-borne illness with high fever and a rash that can be morbilliform or petechial, with characteristic "islands of white in a sea of red".
Juvenile dermatomyositis presents with fever, muscle weakness, and characteristic skin findings like the heliotrope rash and Gottron's papules.
A systemic bacterial infection with fever, migratory polyarthritis, and a characteristic rash of hemorrhagic pustules on an erythematous base on the distal extremities.
A common cause, often presenting as a morbilliform (measles-like) rash that appears 7-10 days after starting a new medication, accompanied by fever.
Infectious mononucleosis causes fever and pharyngitis; a morbilliform rash commonly occurs if the patient is given amoxicillin.
A superficial streptococcal cellulitis with fever and a fiery-red, indurated, and sharply demarcated plaque.
A common viral illness with low-grade fever, oral ulcers, and a vesicular rash on the hands and feet.
A systemic vasculitis in children causing a classic tetrad of palpable purpura on the lower extremities and buttocks, arthritis, abdominal pain, and kidney disease.
Caused by EBV, this presents with fever, pharyngitis, lymphadenopathy, and sometimes a faint morbilliform rash.
The systemic form (Still's disease) is characterized by high, spiking fevers and a distinctive, evanescent, salmon-pink macular or papular rash that appears with the fever.
A childhood vasculitis with prolonged high fever and a constellation of signs: conjunctivitis, oral mucosal changes (strawberry tongue), rash, extremity changes, and cervical lymphadenopathy.
A bacterial illness with high fever and a rash that can be macular, maculopapular, or petechial, often with prominent conjunctival suffusion (red eyes).
A viral illness with high fever, cough, coryza, conjunctivitis, and Koplik's spots, followed by a morbilliform rash that starts on the head and spreads downwards.
A life-threatening bacterial sepsis with fever and a rapidly progressing petechial or purpuric rash that can become necrotic.
A condition in newborns from maternal autoantibodies, causing a characteristic annular, erythematous rash in a periorbital or photosensitive distribution, and potential heart block.
Parvovirus B19 causes Fifth disease, with a "slapped cheek" facial rash followed by a reticular (lacy) rash on the body.
A complication of streptococcal infection causing fever and specific skin signs like erythema marginatum (transient, annular red macules).
Also known as German measles, this is a milder viral illness with fever and a pink maculopapular rash that starts on the face and spreads down, accompanied by posterior auricular lymphadenopathy.
A streptococcal infection with fever and a characteristic "sandpaper" textured rash, a strawberry tongue, and facial flushing with perioral pallor.
A toxin-mediated disease with fever and tender erythroderma followed by widespread superficial blistering and desquamation.
Can present in children with fever and a variety of rashes, most classically the photosensitive malar "butterfly" rash.
A severe toxin-mediated illness with high fever, hypotension, and a diffuse, blanching erythematous rash ("sunburn-like") that later desquamates.
Systemic vasculitides like Kawasaki disease or Henoch-Schönlein purpura are key causes of fever and rash in children.
Acute viral hepatitis (A or B) can be preceded by a serum sickness-like reaction with fever, arthritis, and an urticarial or morbilliform rash.