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Acne agminata

A rare eruption of grouped, reddish-brown papules that can occur in the axilla, but more typically affects the face.

Candidiasis

A yeast infection (intertrigo) presenting as a beefy red, moist rash with characteristic satellite pustules at the border of the main rash.

Darier's disease

A genetic disorder with persistent, greasy, crusted, keratotic papules in a "seborrheic" distribution, including the neck, axillae, and groin.

Dowling-Degos disease

A genetic disorder presenting as a unique pattern of reticulated (net-like) brown-black hyperpigmentation in the skin folds.

Eczema

Atopic dermatitis in children and adults classically presents as itchy, erythematous, and lichenified (thickened) plaques in the flexures (antecubital and popliteal fossae).

Erythrasma

A bacterial infection causing well-demarcated, reddish-brown patches with fine scale in the axillae and groin that fluoresce coral-red under a Wood's lamp.

Fox-Fordyce disease

A rare condition of intensely itchy, skin-colored follicular papules in the axillae and pubic area caused by blockage of apocrine sweat glands.

Hailey-Hailey disease

A genetic blistering disease with painful, recurrent erosions, vesicles, and macerated plaques that form in a "cobblestone" pattern in the neck, axillae, and groin.

Hidradenitis suppuritiva

A chronic inflammatory condition with recurrent, painful, deep-seated nodules, abscesses, sinus tracts, and double-ended comedones in the axillae and groin.

Intertrigo

A general term for inflammation of skin folds due to friction and moisture, presenting as a simple, erythematous, macerated rash.

Inverse lichen planus

A variant of lichen planus that affects intertriginous areas, presenting as violaceous or erythematous plaques that often lack the typical surface scale.

Pseudoxanthoma elasticum

A genetic disorder of elastic fibers, causing small, yellowish, "cobblestone" or "plucked chicken skin" papules in the flexures, especially the neck and axillae.

Psoriasis

Inverse psoriasis presents as well-demarcated, bright red, shiny plaques without the typical silvery scale in the axillae, groin, and under the breasts.

SDRIFE

Symmetrical Drug-Related Intertriginous and Flexural Exanthem is a specific drug reaction causing a symmetric, sharply demarcated, erythematous rash in the gluteal and inguinal folds.

Tinea

A fungal infection of the groin (tinea cruris or "jock itch") presenting as an erythematous, scaling plaque with a raised, active border that spares the scrotum.

Tricomycosis

A bacterial infection of the axillary hair shafts, forming yellow, red, or black concretions or nodules around the hair, but not a rash on the skin itself.

Xanthoma disseminatum

A rare histiocytic disorder with numerous, reddish-yellow or brown papules that coalesce into plaques, with a predilection for flexural areas and mucous membranes.

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