A genetic disorder with multiple, flat-topped, skin-colored, wart-like papules on the backs of the hands and feet.
Chronic vesicular hand eczema can lead to a secondary hyperkeratotic and fissured dermatitis.
Chronic irritant or allergic hand dermatitis often results in a diffuse or patchy pattern of hyperkeratosis, lichenification, and painful fissures.
A general term for marked thickening of the palms and soles, which can be inherited or acquired, and diffuse, focal, or punctate.
A form of punctate keratoderma with multiple, tiny, "raindrop" or "seed-like" hyperkeratotic papules scattered across the palms.
Benign, well-circumscribed, hyperkeratotic, fibrous plaques located over the knuckle joints.
A severe, progressive, diffuse keratoderma with a characteristic erythematous ("transgradiens") border extending onto the tops of the hands.
A diffuse palmoplantar keratoderma associated with severe, early-onset periodontitis leading to premature loss of teeth.
A papulosquamous disorder that causes a characteristic orange-red, waxy keratoderma of the palms and soles.
Palmar psoriasis presents as well-demarcated, erythematous plaques with thick, yellowish, hyperkeratotic scale on the palms.
An inherited keratoderma characterized by multiple, small, discrete, "hard as a nail" keratotic plugs on the palms and soles.
A fungal infection of the hand, often presenting as unilateral, diffuse, fine scaling and hyperkeratosis in the palmar creases ("one hand, two feet" syndrome).
The classic non-epidermolytic diffuse palmoplantar keratoderma, presenting as uniform, waxy, or ivory-colored diffuse thickening of the palms and soles.
