Often acquired from contaminated water ("fishtank granuloma"), this infection typically presents as a localized, crusted nodule or plaque on the hand that can spread up the arm.
Rare on the hands, but can present as a pearly papule with telangiectasias that may ulcerate.
Deposits of calcium in the skin, which can present as hard, white, subcutaneous nodules on the fingertips, especially in systemic sclerosis.
A viral infection from rodents or cats, causing a painful, hemorrhagic or necrotic lesion on the hand or arm.
Infections like sporotrichosis can start as a fixed, ulcerative, or verrucous nodule on the hand at a site of trauma.
A firm, smooth, non-tender cystic structure attached to a tendon sheath or joint, most commonly on the back of the wrist.
Deposits of uric acid crystals forming firm, white-to-yellowish subcutaneous nodules over the joints of the hands.
A viral infection from cattle, causing one or more firm, reddish-blue, painless nodules on the hands, often with a central depression.
A rare systemic disease causing destructive arthritis and characteristic reddish-brown "coral bead" papules around the nail folds.
Infestation of the skin by fly larvae, which can present as a furuncle-like nodule with a central punctum from which the larva breathes.
A viral infection from sheep or goats, presenting as a solitary, firm, reddish papule on the hand that evolves into a large, weeping nodule with a violaceous rim and central umbilication.
Yellowish, flat or slightly elevated plaques within the palmar creases, which are pathognomonic for type III hyperlipoproteinemia.
A benign, rapidly growing vascular proliferation that presents as a bright red, friable, raspberry-like nodule that bleeds very easily, common on the hands.
A firm, non-tender, subcutaneous nodule found over joints and pressure points, such as the knuckles, in patients with rheumatoid arthritis.
A common skin cancer on the sun-exposed dorsal hand, presenting as a crusted, scaly, indurated, and often ulcerated nodule.
Firm, stony-hard, subcutaneous nodules that are attached to tendons, especially the extensor tendons of the hands, seen in familial hypercholesterolemia.
A common, hyperkeratotic, papillomatous growth (verruca vulgaris), often on the hands, which can have thrombosed capillaries appearing as black dots.
