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Acrokeratosis verruciformis of Hopf

A genetic disorder with multiple, flat-topped, skin-colored, wart-like papules on the backs of the hands and feet.

Confluent reticulate papillomatosis of Gougerot and Carteaud

An eruption of small, brownish, hyperkeratotic papules that coalesce into confluent, reticulated (net-like) plaques on the central chest and upper back.

Darier's disease

A genetic disorder with persistent, greasy, crusted, keratotic papules in a "seborrheic" distribution (face, scalp, chest), often with nail abnormalities.

Flegel disease

Also known as hyperkeratosis lenticularis perstans, this is a rare condition with multiple, small, discrete, reddish-brown, hyperkeratotic papules on the tops of the feet and lower legs.

Grover's disease

Also known as transient acantholytic dermatosis, this is an itchy eruption of small, reddish, crusted or keratotic papules on the trunk, often triggered by heat and sweating.

Keratosis pilaris

A very common condition of small, rough, follicular papules ("chicken skin"), often with a central keratotic spine, typically on the upper arms, thighs, and cheeks.

Keratosis punctata

A form of punctate keratoderma with multiple, tiny, "raindrop" or "seed-like" hyperkeratotic papules scattered across the palms and soles.

Lichen planus

Hypertrophic lichen planus is a variant that presents as thick, extremely itchy, hyperkeratotic plaques and nodules, most commonly on the shins.

Lichen spinulosus

A condition with grouped patches of multiple, tiny, follicular papules with a central keratotic spine, feeling like a nutmeg grater.

Perforating collagenosis

A reactive perforating disorder where altered collagen is extruded through the epidermis, presenting as umbilicated, hyperkeratotic papules, often in patients with diabetes or renal failure.

Phrynoderma

Follicular hyperkeratosis caused by severe vitamin A deficiency, presenting as horny, spiny papules on the extensor surfaces of the extremities.

Seborrhoiec keratosis

A common benign tumor of older individuals, presenting as a waxy, hyperkeratotic, "stuck-on" papule or plaque with a verrucous surface.

Viral wart

A common wart (verruca vulgaris) is a hyperkeratotic, papillomatous papule with thrombosed capillaries appearing as black dots.

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