A condition in middle-aged women with asymptomatic, mottled, hypopigmented and hyperpigmented macules on the dorsal forearms.
A rare pigmentary disorder with diffuse hyperpigmentation of the distal extremities (acromelanosis) punctuated by small, confetti-like white spots.
Chronic arsenicism can cause a characteristic "raindrops on a dusty road" pattern of guttate hypopigmentation on a background of diffuse hyperpigmentation.
A rare syndrome of mottled hyper- and hypopigmentation with associated growth and mental retardation.
A genetic disorder characterized by a striking mixture of hyperpigmented and hypopigmented macules on the backs of the hands and feet.
A genetic disorder with a generalized, confetti-like mixture of hyperpigmented and hypopigmented macules covering the entire body.
A variant of cutaneous amyloidosis with a reticulated pattern of hyper- and hypopigmented macules resembling dyschromatosis, but with amyloid deposition.
A rare genetic syndrome with a classic triad of nail dystrophy, oral leukoplakia, and a distinctive, reticulated (net-like) pattern of hyper- and hypopigmentation on the neck and chest.
Severe protein malnutrition can cause a "flaky paint" dermatosis, where patches of hyperpigmented skin peel away to reveal hypopigmented or eroded areas underneath.
A treponemal infection that evolves through stages, resulting in late-stage dyschromic lesions with a mixture of hyperpigmented and achromic (depigmented), atrophic patches.
A dermatologic sign, not a single disease, consisting of a triad of atrophy, telangiectasias, and a mottled pattern of hyper- and hypopigmentation.
Can cause "leukoderma colli" or "necklace of Venus," which is a pattern of small, hypopigmented macules on a hyperpigmented background on the neck.
A rare condition with mottled hyper- and hypopigmentation in a reticular pattern, associated with skeletal and developmental abnormalities.
A genetic DNA repair disorder that leads to severe sun sensitivity and the early development of freckle-like hyperpigmentation and guttate hypopigmentation, creating a mottled appearance.
An X-linked syndrome of congenital deafness and a striking pattern of large, irregular patches of hyper- and hypopigmentation.
