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Cushing's disease

Excess cortisol leads to skin fragility and easy bruising, resulting in petechiae and ecchymoses with minimal trauma.

Gougerot-Blum

A form of pigmented purpuric dermatosis with coalescing, rust-colored macules and lichenoid papules.

Livedoid vasculopathy

A chronic condition with recurrent, painful, punched-out ulcers on the lower legs that is often preceded by purpuric macules.

Majocchi's purpura

A form of pigmented purpuric dermatosis characterized by annular patches of cayenne-pepper-like petechiae and telangiectasias that spread centrifugally.

Rocky Mountain Spotted Fever

A rickettsial disease with a characteristic petechial rash that begins on the wrists and ankles and spreads centrally, involving the palms and soles.

Schamberg's disease

The most common pigmented purpuric dermatosis, presenting as chronic, irregular patches of cayenne-pepper-like petechiae on the lower legs.

Scurvy

Vitamin C deficiency leading to impaired collagen synthesis, characterized by distinctive perifollicular hemorrhage (petechiae around hair follicles) and corkscrew hairs.

Thrombocytopenia

A low platelet count causing widespread, non-palpable petechiae that are not associated with inflammation.

Thrombotic thrombocytopenic purpura

A serious condition of microvascular thrombosis, causing fever, neurologic symptoms, and a widespread petechial rash.

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