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Atrophoderma of Pasini and Pierini

Characterized by large, asymptomatic, sharply demarcated 'cliff-drop' patches of dermal atrophy with a bluish-brown hue and no sclerosis, distinguishing it from morphea.

Burn

A deep burn heals with a hypertrophic or keloidal scar that is firm, indurated, and contracted.

Carcinoma en cuirasse

A rare form of cutaneous metastasis, typically from breast cancer, where the skin of the chest becomes diffusely infiltrated, sclerotic, and board-like.

Eosinophilic fasciitis

A rare scleroderma-like disorder with rapid onset of symmetric, painful swelling and induration of the limbs, sparing the hands and feet, and associated with peripheral eosinophilia.

Extragenital Lichen sclerosus

Presents as atrophic, porcelain-white plaques, which are less indurated than morphea.

Keloid

An overgrowth of scar tissue that extends beyond the borders of the original wound, forming a firm, rubbery, indurated nodule or plaque.

Lichen amyloid

A form of primary cutaneous amyloidosis with intensely pruritic, hyperkeratotic papules that coalesce into thickened, indurated, brownish, rippled plaques on the shins.

Lupus profundus

A panniculitis presenting as firm, deep, subcutaneous nodules that are indurated but heal with a characteristic depressed scar.

Macular amyloid

A form of primary cutaneous amyloidosis with pruritic, grayish-brown macules that have a rippled pattern, which is not typically indurated.

Morphea

A form of localized scleroderma presenting as a well-demarcated, indurated, sclerotic plaque that becomes ivory-white and atrophic, often with a lilac-colored border.

Necrobiosis lipoidica diabeticorum

A condition on the shins where plaques develop a distinct waxy, yellow, atrophic center with a raised, indurated border.

Nephrogenic fibrosing dermopathy

A fibrosing disorder in patients with renal failure exposed to gadolinium, causing symmetric, woody induration and brawny hyperpigmentation of the limbs.

POEMS syndrome

A paraneoplastic syndrome where skin changes include diffuse hyperpigmentation, hypertrichosis, and skin thickening or sclerosis.

Pretibial myxedema

A manifestation of Graves' disease, with symmetric, non-pitting, firm, indurated plaques and nodules on the shins with a peau d'orange texture.

Scleredema

A condition with symmetric, non-pitting, woody induration of the skin, typically starting on the neck and upper back, without the papules of scleromyxedema.

Sclerodermatoid graft versus host disease

A chronic form of GVHD that closely mimics systemic sclerosis, with hidebound, sclerotic skin and joint contractures.

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