Presents in infants with a sudden onset of large, annular or targetoid purpuric plaques on the face and extremities, along with non-pitting edema.
Presents as tender subcutaneous nodules on extensor surfaces and palpable purpura in patients with a history of asthma and eosinophilia.
Recurrent crops of palpable purpura on the lower legs are the hallmark, often leading to ulceration and necrosis in cold-exposed areas.
Palpable purpura appears symmetrically on dependent areas 7-10 days after starting a new medication.
Persistent, firm, red-to-violaceous papules, plaques, and nodules are characteristically located symmetrically over extensor surfaces and joints.
Palpable purpura is classically distributed over the buttocks and lower extremities of children, often accompanied by arthritis, abdominal pain, and nephritis.
Palpable purpura is the most common manifestation, but splinter hemorrhages and digital infarcts are also characteristic features.
Tender subcutaneous nodules along the course of arteries, livedo reticularis, and 'starburst' purpura are the most characteristic skin findings.
Cutaneous signs are rare, but can include tender, erythematous nodules resembling erythema nodosum, typically over the shins.
Presents as painful or burning urticarial lesions that persist for more than 24 hours and resolve leaving purpuric stains.
Palpable purpura is common, but a specific 'strawberry gum' gingivitis and destructive nasal or oral ulcerations are highly characteristic.
