A nodular BCC is typically pearly with a rolled border and telangiectasias, while a lymphoma presents as a firmer, flesh-colored or violaceous nodule without these features.
This often presents as a chronic, suppurative nodule that may ulcerate, and can be diagnosed with culture, unlike the solid tumor of a lymphoma.
This benign tumor is distinguished by the "dimple sign" (retracting with lateral pressure), which is absent in a cutaneous lymphoma nodule.
This is a very firm, plaque-like tumor that is fixed to the underlying tissue, whereas a B-cell lymphoma is typically a more discrete, rubbery nodule.
A keloid is a firm, fibrous scar that arises at a site of previous trauma, a history that is usually absent for a primary cutaneous lymphoma.
A KA is characterized by its rapid growth into a crater-like nodule with a central keratin plug, a morphology not seen in B-cell lymphoma.
While clinically identical, a skin metastasis is distinguished by identifying a primary internal malignancy, whereas primary cutaneous lymphoma originates in the skin.
This often presents as a chronic, slow-growing nodule that can break down and ulcerate ("scrofuloderma"), and is diagnosed by specific staining and culture.
This is a benign vascular tumor that is bright red, friable, and bleeds easily, unlike the firm, non-vascular nature of a lymphoma nodule.
A nodular SCC is typically a firm, hyperkeratotic, or ulcerated nodule arising on sun-exposed skin, whereas a lymphoma is usually a smooth, non-scaly nodule.
