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Actinic keratosis

An AK is a rough, scaly patch and is typically not tender, whereas CNH is a discrete, smooth nodule defined by its exquisite tenderness on pressure.

Basal cell carcinoma

A nodular BCC on the ear is typically a pearly papule that may ulcerate but characteristically lacks the intense pain of CNH.

Calcinosis cutis

This presents as a hard, rock-like deposit within the skin, much firmer on palpation than the inflamed nodule of CNH.

Chilblain

Chilblains are violaceous, itchy plaques that appear on acral sites in response to cold, a different trigger and morphology than the single, pressure-related nodule of CNH.

Gouty tophi

A tophus on the ear is a deposit of uric acid crystals, which can be confirmed by finding crystals on aspiration, and is associated with a history of gout.

Squamous cell carcinoma

An SCC on the ear is a firm, indurated, and often ulcerated or crusted nodule that is typically not as exquisitely tender as CNH.

Viral wart

A wart has a verrucous (cauliflower-like) surface, unlike the smooth, dome-shaped nodule of CNH.

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