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Arsenical keratoses

These are multiple, small, yellowish, hyperkeratotic papules on the palms and soles, distinguished by a history of arsenic exposure.

Corn

A corn is a very localized, painful, cone-shaped area of hyperkeratosis over a bony prominence, unlike the diffuse thickening of a keratoderma.

Knuckle pads

These are a specific type of keratoderma, distinguished by their location as circumscribed, fibrous thickenings over the finger joints.

Psoriasis

Palmoplantar psoriasis is characterized by well-demarcated, erythematous plaques with a thick, silvery scale, a more inflammatory picture than simple keratoderma.

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