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Atypical naevus

An atypical nevus is typically smaller and more papular than the large, flat, slowly expanding patch of a lentigo maligna on sun-damaged skin.

Congenital melanocytic naevus

A CMN is present from birth, whereas a lentigo maligna is an acquired lesion of older, sun-damaged skin.

Junctional naevus

A simple junctional nevus is small, symmetric, and uniform in color, lacking the large size, irregular shape, and color variegation of a lentigo maligna.

Lentigo

A simple solar lentigo ("sun spot") is a small, uniformly tan-to-brown macule that is stable, whereas a lentigo maligna is characterized by its slow but persistent growth and development of color variegation.

Melanoma

Lentigo maligna is a subtype of melanoma (in situ), but it is distinguished from invasive lentigo maligna melanoma by being completely flat, without any palpable or nodular component.

Melanoma in situ

Lentigo maligna is a specific type of melanoma in situ, defined by its occurrence on chronically sun-damaged skin, particularly the head and neck.

Pigmented basal cell carcinoma

A pigmented BCC may look like a dark patch, but it will often have subtle clues of a BCC, such as a pearly or translucent quality at the border.

Seborrhoiec keratosis

A flat, pigmented SK (solar lentigo) can mimic early LM, but it often develops a waxy or verrucous texture over time.

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