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Atrophic lichen planus

This results in atrophic, whitish patches, whereas macular amyloidosis is a purely hyperpigmented, non-atrophic condition.

Erythema dyschromicum perstans

Also known as ashy dermatosis, this presents as asymptomatic, slate-grey to blue-brown patches, often with a thin, raised, erythematous border initially, which is not a feature of macular amyloidosis.

Notalgia paresthetica

This is a sensory neuropathy causing intense itching on the back, which then leads to a patch of post-inflammatory hyperpigmentation; macular amyloidosis is a primary deposition of amyloid.

Postinflammatory hyperpigmentation

This is distinguished by a clear history of a preceding inflammatory condition (like eczema or acne), whereas macular amyloidosis arises de novo.

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