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Aging

Senescent alopecia is a diffuse, global thinning of hair density, whereas MPHL follows a very specific pattern of bitemporal recession and vertex thinning.

Hypothyroidism

Hair loss from hypothyroidism is a diffuse, non-patterned process, unlike the distinct pattern of MPHL.

Iron deficiency

This causes diffuse, non-scarring hair loss and is not confined to the classic androgen-dependent pattern of MPHL.

Lichen planopilaris

LPP is a scarring alopecia, distinguished by perifollicular inflammation and permanent loss of follicles, whereas MPHL is a non-scarring process of hair miniaturization.

Telogen effluvium

TE is an acute, diffuse shedding event following a stressor, a different history and presentation than the slow, progressive, patterned thinning of MPHL.

Traction alopecia

This is distinguished by a history of tight hairstyles and hair loss localized to the areas of tension, not the classic vertex/temporal pattern of MPHL.

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