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Contact dermatitis

This is a superficial, eczematous inflammation, not the deep, atrophic, waxy plaque of necrobiosis lipoidica.

Diabetic dermopathy

These are multiple, small, atrophic, hyperpigmented macules on the shins ("shin spots"), a much more subtle finding than the large, waxy plaque of NL.

Lipodermatosclerosis

This is a fibrosing panniculitis of the lower leg due to venous insufficiency, presenting with indurated, bound-down skin and an "inverted champagne bottle" shape, not a yellowish, waxy plaque.

Morphea

A morphea plaque is sclerotic and firm (ivory-colored), lacking the characteristic yellowish hue, atrophy, and prominent telangiectasias of NL.

Psoriasis

A psoriatic plaque is distinguished by its thick, silvery scale and lack of atrophy or yellow color.

Sarcoidosis

A plaque of sarcoidosis is reddish-brown and lacks the waxy atrophy and prominent telangiectasias seen in NL.

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