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Arterial ulcer

An arterial ulcer is caused by ischemia, characterized by a "punched-out" appearance, pale base, and associated signs of arterial insufficiency (e.g., absent pulses, coolness), and is typically very painful.

Necrobiosis lipoidica

This begins as a waxy, yellowish plaque that may later ulcerate, a different primary morphology than a primary neuropathic ulcer.

Pyoderma gangrenosum

This is an inflammatory ulcer distinguished by its rapid expansion and characteristic violaceous, undermined border.

Venous ulcer

A venous ulcer is located in the "gaiter area" above the medial ankle and is surrounded by signs of chronic venous disease like edema and hemosiderin staining, a different location and context than a pressure-point neuropathic ulcer.

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