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Acne

Distinguished by the presence of comedones (blackheads and whiteheads), which are absent in rosacea.

Acne vulgaris

Characterized by comedones, papules, pustules, and cysts, typically affecting a younger age group, whereas rosacea lacks comedones.

Acute lupus erythematosis

Presents with a 'malar rash' that characteristically spares the nasolabial folds and is associated with systemic symptoms and positive ANA serology.

Airborne allergic contact dermatitis

Often involves the eyelids and upper cheeks with significant pruritus and ill-defined erythema, related to environmental allergens.

Discoid lupus erythematosis

Presents as well-demarcated, atrophic, scaly plaques with follicular plugging, often leading to scarring, which is not a feature of rosacea.

Drug phototoxicity

An exaggerated sunburn reaction in sun-exposed areas following systemic medication intake, with a clear history of a new photosensitizing drug.

EGFR inhibitors

Cause an acneiform eruption of monomorphic papules and pustules, but unlike rosacea, these are not associated with background erythema or telangiectasias.

Haber's syndrome

A rare genodermatosis featuring a rosacea-like facial eruption but also characterized by pitted scars and keratotic papules on the trunk and limbs.

Lupus vulgaris

A form of cutaneous tuberculosis presenting as reddish-brown 'apple-jelly' nodules on diascopy (pressing with a glass slide).

Morbihan's disease

Presents as solid, persistent facial edema and erythema, primarily affecting the upper half of the face, representing a severe, lymphedematous form of rosacea.

Perioral dermatitis

Characterized by monomorphic papules and pustules clustered around the mouth, nose, and eyes, with a classic zone of sparing around the vermilion border of the lips.

Pityriasis folliculorum

Caused by an overgrowth of Demodex mites, presenting with perifollicular scaling and a rough, sandpaper-like texture to the skin.

Polymorphic light eruption

An itchy eruption of papules or plaques that appears hours to days after sun exposure and resolves without the persistent erythema of rosacea.

Rosaceiform dermatitis

A descriptive term for eruptions that mimic rosacea but are caused by other factors, like topical steroids or other medications.

Sarcoidosis

Can present with facial papules, but these are often reddish-brown or violaceous and firm, and biopsy shows non-caseating granulomas.

Seborrhoiec dermatitis

Distinguished by its greasy, yellowish scale and location in sebaceous areas like the nasolabial folds, eyebrows, and scalp, rather than the central facial erythema of rosacea.

Steroid overuse

Causes a rosacea-like eruption with prominent telangiectasias and atrophy, directly related to the application of topical corticosteroids.

Subacute lupus erythematosis

Presents as annular or papulosquamous plaques in a photosensitive distribution, associated with positive anti-Ro/SSA antibodies.

Sunburn

An acute, painful erythema following excessive UV exposure, which resolves, unlike the chronic nature of rosacea.

Tinea faciale

An asymmetric, annular patch with a scaly, active border, confirmed by a positive KOH preparation, distinguishing it from the symmetric erythema of rosacea.

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