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Adenovirus

More likely to be accompanied by significant respiratory symptoms like pharyngitis and conjunctivitis.

CMV

Can cause a mononucleosis-like syndrome with a rash, but is distinguished by a negative heterophile antibody test.

EBV

Causes infectious mononucleosis, which typically features more severe pharyngitis, fatigue, and splenomegaly than rubella.

Enterovirus

Often presents with a specific rash distribution, such as hand-foot-and-mouth disease, which is not characteristic of rubella.

HIV

Acute retroviral syndrome can present with a morbilliform rash, but is also associated with fever, myalgias, and oral ulcers, and is confirmed by HIV testing.

Measles

Distinguished by a more severe prodrome of high fever, cough, coryza, conjunctivitis, and the pathognomonic Koplik spots before the rash appears.

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