Painful, shallow ulcers with an erythematous halo located on non-keratinized oral mucosa, unlike the painless mucous patches of syphilis.
Presents as multiple, reddish-brown or violaceous papules in the anogenital region, histologically a form of carcinoma in situ associated with HPV.
Coin-shaped, intensely pruritic, eczematous plaques, which are not typical of the non-pruritic, papulosquamous rash of syphilis.
A morbilliform rash that is typically more pruritic and widespread, with a clear history of a new medication, and lacks palm/sole involvement.
Presents as pustules centered on hair follicles, whereas syphilitic folliculitis causes 'moth-eaten' alopecia without prominent pustulation.
Exophytic, cauliflower-like papules in the anogenital region caused by HPV, unlike the flat, broad, and moist condyloma lata of syphilis.
Characterized by small, 'drop-like' salmon-pink papules with a fine scale, often triggered by a streptococcal infection.
A viral illness causing vesicles on the hands, feet, and in the mouth, typically in young children, unlike the papulosquamous eruption of syphilis.
Distinguished by its pruritic, purple, polygonal papules, often with Wickham's striae, a different morphology and color than syphilitic papules.
Presents as crops of small, reddish-brown papules with an adherent 'mica-like' scale that can be scraped off, typically on the trunk.
Begins with a single 'herald patch' followed by a generalized eruption of oval, pink papules with fine scale in a 'Christmas tree' distribution on the back.
Can present as non-healing genital ulcers (chancre-like) but are typically solitary and indurated, and biopsy confirms malignancy.
A generalized maculopapular rash that is typically more transient and associated with acute viral symptoms, and rarely involves the palms and soles.
