Characterized by classic 'target' lesions, often acrally distributed and frequently triggered by herpes simplex infection, with less severe mucosal involvement than SJS.
Widespread infection (eczema herpeticum) can cause erosions, but is distinguished by a positive viral culture or PCR and lacks the dusky, atypical targets of SJS.
A chronic autoimmune blistering disease primarily affecting mucosal surfaces, leading to scarring, unlike the acute, drug-induced nature of SJS.
An autoimmune blistering disease causing flaccid bullae and erosions due to autoantibodies against desmogleins, confirmed by immunofluorescence.
Considered a more severe variant of the same disease process, distinguished by a larger body surface area of epidermal detachment (>30%).
