Nicotinamide

By Dr Magnus Lynch
MA(Cantab) DPhil(Oxon) MRCS FRCP
Consultant Dermatologist & Dermatological Surgeon
Last updated 2025-09-10

Clinical studies have found that taking oral nicotinamide (a form of B vitamin that can be purchased without prescription) at a dose of 500 mg twice daily may reduce the risk of new non-melanoma skin cancers (such as basal cell carcinoma and squamous cell carcinoma) in individuals with a history of these cancers. It may also reduce the occurrence of actinic keratoses (precancerous lesions).

Nicotinamide is generally well tolerated but common side effects include gastrointestinal symptoms like nausea and upset stomach, as well as flushing and headaches. Prolonged use of high doses (over 3 grams per day) can lead to liver toxicity, potentially causing jaundice. Rare side effects include low blood pressure and allergic reactions. As for all medications you should carefully read the product information leaflet that comes with the medicine so that you are aware of all potential side effects.

About Dr Magnus Lynch

MA(Cantab) DPhil(Oxon) MRCS FRCP

I am a London-based Consultant Dermatologist and Dermatological Surgeon. I am highly experienced in skin cancer diagnosis, Mohs micrographic surgery, acne, rosacea, acne scarring and laser treatments. I studied at the Universities of Cambridge and Oxford, and completed my dermatology training and Mohs fellowship at the prestigious St John's Institute of Dermatology. I graduated from medical school in 2003 and have worked exclusively in Dermatology since 2012.

I lead a research team at King's College London investigating the molecular biology of skin cancer. In recent years I have been involved in Media Appearances, including the Channel 5 series 'Skin A&E', where I perform skin surgeries and treat various skin conditions.

My NHS practice is at Guy's Hospital. I consult with private patients at OneWelbeck (near to Bond Street station) and on Harley Street. Book A Consultation.