What skincare routine should you use during isotretinoin treatment?

By Dr Magnus Lynch
MA(Cantab) DPhil(Oxon) MRCS FRCP
Consultant Dermatologist & Dermatological Surgeon

Isotretinoin (roaccutane) causes significant changes to the biology of the skin resulting in significant dryness. This dryness is one of the most common side effects of the treatment and can be unexpected for those with acne-prone skin which tends to be greasy.

Whether you are just about to start a course of Isotretinoin or have been taking for some weeks, here are our recommendations for skin care products to ease dryness of the skin, chapped lips and eyes.

It is important to start your routine with a non-comedogenic cleanser. It is not essential to spend a lot of money - we like La Roche Posay Toleriane Dermo-Cleanser and Foaming Gel Cleanser. Cleansers produced by CeraVe and Cetaphil are also effective and inexpensive.

You may need to use a moisturiser due to skin dryness. Again the key here is to use a non-comedogenic products. We like La Roche Posay Effaclar H.

Finally, almost everyone will experience dry lips and the key here is to apply a lip balm as often as possible. We like Elizabeth Arden Eight hour intensive lip balm. Cheaper - but still effective - options include eucerin intensive lip balm or good old vaseline.

Dr. Magnus Lynch, Consultant Dermatologist

About Dr Magnus Lynch

I am a London-based Consultant Dermatologist and Dermatological Surgeon. I am highly experienced in skin cancer diagnosis, Mohs micrographic surgery, acne, rosacea, acne scarring and laser treatments. I studied at the Universities of Cambridge and Oxford, and completed my dermatology training and Mohs fellowship at the prestigious St John’s Institute of Dermatology. I graduated from medical school in 2003 and have worked exclusively in Dermatology since 2012.

I lead a research team at King’s College London investigating the molecular biology of skin cancer. In recent years I have been involved in Media Appearances, including the Channel 5 series 'Skin A&E', where I perform skin surgeries and treat various skin conditions. Filming for the next series has recently completed and the series will be released later in 2025.

My NHS practice is at Guy's Hospital. I consult with private patients at the London Bridge Hospital, OneWelbeck (near to Bond Street station) and on Harley Street. A new consultation is £250. Book A Consultation.

I am the founder of Revessa Health which provides online consultations for acne and rosacea across the UK (see below).

What skincare routine should you use during isotretinoin treatment?

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